Save time with these metabolic health research portals

by Cecile Seth · Published April 5, 2021 · Updated February 7, 2024

We’re celebrating our Organizing Research team launching a big project with Metabolic Multipliers Sarah Rice & Nutrition Network.

References Resource – Therapeutic Carbohydrate Restriction

Each curated by 40+ conditions with a metabolic component as follows.

Potential Targets of Reduced-Carbohydrate Therapies. 40+ conditions

Curated References Resource – Therapeutic Carbohydrate Restriction
- Top 2,000+ studies in humans.
- Downloadable handouts – 7 by condition. Research round ups for proceeding 3 months
Metabolic Multiplier group library on Zotero.org
- 4,600+ studies in humans
- Group library in popular citation manager, Zotero.org
- Includes all studies in #1 above. Sophisticated search capabilities
Keto Science Database group library on Zotero.org
- 13,500+ citations in humans & animals
- Includes protein’s integral role in driving human evolution

Zotero.org is a popular citation manager that facilitates public sharing of large bodies of research. It also provides sophisticated search capabilities.

1. References Resource – Therapeutic Carbohydrate Restriction

Can you name 40+ medical conditions with a metabolic component? Would you like curated research on each? Well it is here, “References Resource – Therapeutic Carbohydrate Restriction.”

Tailor metabolic interventions to each patient’s bio-individuality

Therapeutic carbohydrate reduction targets metabolic disorders. Pediatric and adult ketogenic diet therapies target neurological conditions. See our Best resources for an overview of keto diet therapies.

Other conditions which may have features of metabolic dysregulation have protocol variations emerging to augment existing therapies. E.g. migraines, inflammation, cancer, and polycystic kidney disease.

As we learn more about the gut microbiome’s complexity will new, tailored protocols continue to emerge?

Printable downloads for 7+ common conditions

Of particular interest might be the printable downloads of curated research by topic: obesity, type 2 diabetes, cardiovascular disease, hypertension, NAFLD, menopause, and Autism Spectrum Disorder & ADHD. Others in the works.

Curated round up of last 3 month’s research

Looking for a curated list of each month’s new research? The download section (above) includes that too for the last 3 months. Hoping it will save us all time.

Target audience – Convincing a curious clinicians & scientists

We hope you’ll find this resource useful in convincing the “curious.” Share with colleagues who want to see evidence of the efficacy of lifestyle change for promoting metabolic health. So, if a busy clinician specializing in condition X were to only read one study about condition Y, we help them out by putting the most interesting paper at the top.

This resource is best viewed by browsing sections and search very basic. For sophisticated search see #2 and #3 below

Thank our Metabolic Multiplier’s team volunteers

Scholarship courtesy of volunteer Sarah Rice, BSc.(Hons) MCOptom (Optometrist – UK). Professional formatting and hosting thanks to Nutrition Network. Twitter
Organizing Research team – Philip Ovadia, MD (this cardiologist’s input on the cardiovascular disease handout was invaluable), Travis Statham, Sarah Rice & Cecile Seth worked on organization.
Clinical Protocols & Toolkits Team – for reviewing how we’re organizing this information. For visuals & details see our metabolic health schematics

Want better search capability, more studies, & less curation?

Your time is precious. So, we’ve also made 2 more complete reference libraries available as public Zotero groups. The search function & tagging in the Zotero version is much more robust than in “References Resource – Therapeutic Carbohydrate Restriction” to assist with your own search interests! Zotero’s search function often accesses the entire abstract rather than title and author assigned tags

Perhaps most importantly, Sarah & Travis are doing the hard work of keeping these databases up to date. We extend a hearty thanks to them both for their on going community service!

We look forward to continuing to curate & amplify the excellent work of metabolic health thought leaders!

2. Metabolic Multiplier group library on Zotero.org

4,600+ studies in humans
Low-Carbohydrate Nutrition
Curated by 40+ conditions
Group library in popular citation manager with powerful search

Zotero group Metabolic Multiplier – Sarah’s (& Cecile’s) complete library of 4,200+ references available. (References Resource – Therapeutic Carbohydrate Restriction in #1 has a subset of ~ 2,000 references. These are tagged in this source library).

3. Search 13,500+ studies related to metabolic health, diets, and evolution

13,500+ citations in humans & animals
Low-Carbohydrate Nutrition
Curated by 40+ conditions
Group library in popular citation manager
Includes protein’s integral role driving human evolution, biology, toxicology, anthropology, archeology, & evolution

Zotero group Keto Science Database brings together many Zotero and Mendeley collections while also using references from popular books, the r/KetoScience subreddit itself (scrape, parse, automate) using Pushshift.io.

Courtesy of Metabolic Multiplier Travis Statham, an administrator of 50+ subreddits.

Other curated research repositories

While each of these may be smaller, we appreciate their generously sharing their scholarship! We’ve combined all of these above.

Ketoscience sub-reddit

The r/ketoscience subreddit members share and discuss the latest research with its 330,000+ members. They also host active “ask me anythings” (AMA’s). Have aligned categories and tags with our Metabolic schematics. Administrators (including Metabolic Multiplier Travis Statham) seem to cover similar research alerts as Nutrition Network‘s Low Carbohydrate research portal

Atkins

Read over 150 peer-reviewed studies from major scientific publications that support the principles of the Atkins Diet. The abstract is listed for review, as well as a link to the full publication on PubMed. Part of their Health Care Professionals portal (Atkins HCP)

Public Health Collaboration: Informing Healthy Decisions

Randomised controlled trials comparing low-carb diets of less than 130g carbohydrate per day to low-fat diets of less than 35% fat of total calories with participants living with Type 2 Diabetes. Public Health Collaboration is a respected UK registered charity. (See our foundations supporting metabolic health to better understand the landscape.)

MEATrition & Revero (which was MeatRx)

Developed over 50 categories of research supporting meat-based nutrition. These studies also appear in #3 the Zotero group Keto Science Database on Zotero and #4 Ketoscience subreddit. We thank Travis Statham for his scholarship. Travis is enrolled in Graduate School in Utah State’s Nutrition Dietetics & Food Sciences program. Doing research or conducting a clinical trial? See his more detailed information on MEATrition.

The Fasting Method

Studies supporting intermittent fasting as a dietary intervention. They are updating their website and we will update with a link once it becomes available. Sources #1 Nutrition Network‘s Low Carbohydrate Nutrition research portal, #2 Zotero group Metabolic Multiplier, and #3 Zotero group Keto Science Database above also include sections on fasting based on The Fasting Method’s excellent scholarship and generosity towards the metabolic health community. We thank them for their scholarship.

Medical ketogenic diet for metabolic and mental health research

Psychiatrist & Harvard Medical School professor Chris Palmer, MD’s bibliography as he explores the mental – metabolic health connection. We thank Dr. Palmer for his scholarship.